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Hints for the possibility of two times emerged in M-theory in 1995. If taken seriously this required new concepts that could solve unitarity (ghost) and causality problems so that physics could be described sensibly in a spacetime with two times. The necessary concept turned out to be a gauge symmetry in phase space. This is an unfamiliar concept, but is one that extends Einstein's approach to the formulation of fundamental equations of physics, by removing the perspective of the observer, not only in position space but more generally in phase space. This approach led in 1998 to what is now called 2T-physics, which has been formulated so far in classical and quantum mechanics, field theory and partially in string theory. In this lecture I will explain the fundamental aspects of 2T-physics, and will outline the progress from classical mechanics, through the standard model and gravity, all the way to supergravity in d-space plus 2-time dimensions. I will describe how 2T-physics is consistent with 1T-physics in (d-1)-space plus 1-time dimensions, but also how it goes beyond 1T-physics, by making in principle a vast number of verifiable predictions that are systematically missed in 1T-physics, as well as providing new computational tools for physics.

The D0 Collaboration recently reported a 3.2sigma deviation from the standard model prediction in the like-sign dimuon asymmetry. I will discuss the implications of this anomaly assuming that new physics contributes only to B_{d,s} mixing. The data allow universal new physics with similar contributions relative to the SM in the B_d and B_s systems, but favors a larger deviation in B_s than in B_d mixing. The general minimal flavor violation framework with flavor diagonal CP violating phases can account for the former and remarkably even for the latter case. This observation makes it simpler to speculate about which extensions with general flavor structure may also fit the data.