Talks by Benoit Palmieri

Phase-field model for cellular monolayers : a cancer cell migration studyauthors : Benoit Palmieri and Martin Grant

Benoit Palmieri McGill University
Recent experimental work [1] suggests that the increased motility of cancer cells observed in a confluent monolayer of normal cells is due to the mechanical mismatch between the two cell types. The soft cancer cell undergoes large deformations and can squeeze between small channels defined by the space between the normal cells. We developed a phase-field model description of cellular monolayers to study such a process. The system is setup as a free-boundary problem where each cell is a highly deformable soft body [2].