PIRSA:13120020

How are cell concentrations implicated in activity and selectivity of antimicrobial peptides?

APA

Bagheri, A. (2013). How are cell concentrations implicated in activity and selectivity of antimicrobial peptides?. Perimeter Institute. https://pirsa.org/13120020

MLA

Bagheri, Azadeh. How are cell concentrations implicated in activity and selectivity of antimicrobial peptides?. Perimeter Institute, Dec. 05, 2013, https://pirsa.org/13120020

BibTex

          @misc{ pirsa_13120020,
            doi = {10.48660/13120020},
            url = {https://pirsa.org/13120020},
            author = {Bagheri, Azadeh},
            keywords = {},
            language = {en},
            title = {How are cell concentrations implicated in activity and selectivity of antimicrobial peptides?},
            publisher = {Perimeter Institute},
            year = {2013},
            month = {dec},
            note = {PIRSA:13120020 see, \url{https://pirsa.org}}
          }
          

Azadeh Bagheri University of Waterloo

Abstract

Antimicrobial peptides (AMPs) are known to be active against a wide range of microbes. Cell selectivity is an important quality of AMPs which enables them to preferentially bind to and kill the microbes over host cells. Despite its significance in determining the cell selectivity however the cell-concentration dependence of AMP activity has not been criticality examined. Here we present a coarse-grained model for describing how cell concentrations are implicated in AMP's membrane-perturbing activity and selectivity.